Table 3:
Primary and moderation model estimates of risk difference in anxiety symptom reduction among patients with at least moderate anxiety symptoms a trial of a collaborative care model for treatment of depression and diabetes in India (n=172)
| 6 months | 12 months | 18 months | 24 months | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| RD | SE | p | RD | SE | p | RD | SE | p | RD | SE | p | |
| Primary Analysis 1 | ||||||||||||
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| Control | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Intervention | 0.17 | 0.07 | 0.02 | 0.23 | 0.07 | 0.002 | 0.13 | 0.07 | 0.06 | −0.02 | 0.05 | 0.68 |
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|
Moderators
2
| ||||||||||||
| Age | ||||||||||||
| 35-49 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| 50-64 | 0.08 | 0.16 | 0.61 | −0.11 | 0.16 | 0.48 | 0.26 | 0.16 | 0.10 | 0.29 | 0.12 | 0.02 |
| 65+ | −0.35 | 0.29 | 0.23 | 0.07 | 0.25 | 0.79 | 0.39 | 0.22 | 0.08 | 0.50 | 0.17 | 0.004 |
|
| ||||||||||||
| Sex | ||||||||||||
| Male | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Female | −0.01 | 0.17 | 0.96 | −0.04 | 0.16 | 0.81 | 0.16 | 0.14 | 0.25 | −0.01 | 0.12 | 0.95 |
|
| ||||||||||||
| Marital Status | ||||||||||||
| Unmarried | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Married | 0.00 | 0.19 | 0.99 | 0.09 | 0.21 | 0.65 | −0.19 | 0.20 | 0.35 | −0.01 | 0.14 | 0.94 |
|
| ||||||||||||
| Education | ||||||||||||
| No Education/Unsure | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Primary/Secondary | −0.11 | 0.28 | 0.71 | 0.06 | 0.26 | 0.82 | −0.21 | 0.18 | 0.22 | −0.20 | 0.25 | 0.42 |
| Post-Secondary | −0.06 | 0.32 | 0.84 | −0.27 | 0.30 | 0.37 | −0.23 | 0.22 | 0.30 | −0.08 | 0.26 | 0.77 |
|
| ||||||||||||
| Monthly Household Income | ||||||||||||
| <10,000 INR | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| 10,001-20,000 INR | −0.13 | 0.19 | 0.51 | −0.08 | 0.20 | 0.67 | −0.01 | 0.18 | 0.97 | −0.13 | 0.14 | 0.34 |
| >20,000 INR | 0.09 | 0.18 | 0.62 | −0.17 | 0.18 | 0.34 | 0.03 | 0.17 | 0.86 | −0.04 | 0.13 | 0.73 |
|
| ||||||||||||
| HbA1C | ||||||||||||
| <8% | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| ≥8% | −0.15 | 0.19 | 0.43 | −0.12 | 0.18 | 0.49 | −0.29 | 0.16 | 0.08 | −0.06 | 0.11 | 0.61 |
|
| ||||||||||||
| PHQ-9 | ||||||||||||
| Moderate | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Moderately Severe or Severe | 0.12 | 0.15 | 0.43 | 0.18 | 0.15 | 0.22 | 0.19 | 0.14 | 0.17 | 0.10 | 0.11 | 0.36 |
|
| ||||||||||||
| GAD-7 | ||||||||||||
| Moderate | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Severe | 0.24 | 0.15 | 0.11 | 0.15 | 0.15 | 0.30 | 0.07 | 0.13 | 0.58 | −0.12 | 0.11 | 0.26 |
Abbreviations: RD, risk difference. SE, standard error. INR, Indian Rupees. A1C, HbA1C, Hemoglobin A1C. SCL-20, Symptoms Checklist Depression Scale.
Footnotes:
1
Treatment × time interaction effect
2
Treatment × time × moderator interaction effect.
Bold text indicates statistically significant estimate (p < 0.05).