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. 2014 Jul 21;2014(7):CD009285. doi: 10.1002/14651858.CD009285.pub3

Yin 2010.

Methods Design: 12 week, multicentre, randomised, double‐blind, placebo‐controlled study
Participants Population: 205 patients with stable stage I or II COPD
Interventions 1. Tiotropium 18 mcg once daily
2. Placebo
Outcomes Clinical symptoms, adverse events
Notes  

COPD: chronic obstructive pulmonary disease
 FEV1: forced expiratory volume in one second
 FVC: forced vital capacity
 6MWD: six‐minute walk distance