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| Methods | Design: 12 week, multicentre, randomised, double‐blind, placebo‐controlled study |
| Participants | Population: 205 patients with stable stage I or II COPD |
| Interventions |
1. Tiotropium 18 mcg once daily 2. Placebo |
| Outcomes | Clinical symptoms, adverse events |
| Notes |
COPD: chronic obstructive pulmonary disease FEV1: forced expiratory volume in one second FVC: forced vital capacity 6MWD: six‐minute walk distance
