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. 2021 Jul 24;50(5):2923–2937. doi: 10.1093/nar/gkab615

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — The 1.9 Å crystal structure of Ssd1 reveals conservation of fold with RNase II enzymes. (A) Comparison of domain structures of Ssd1 and the related proteins Rrp44 (Dis3, numbering is for yeast) and Dis3L2 (numbering is for mouse). Boxes indicate folded domains with separating grey lines indicating natively unstructured regions. Black boxes equate to features coloured black in the structural figures. (B) Structure of Ssd1 observed from three different viewpoints: N-terminal side view, front view and C-terminal side view. The domains are coloured to match those in (A).