Table 2.
Hemodynamic parameters in Sham and pulmonary artery-banded rats
| Hemodynamics | Sham |
PAB |
||||
|---|---|---|---|---|---|---|
| Intact male | Intact female | OVX female | Intact male | Intact female | OVX female | |
| Peak systemic pressure, mmHg | 110 ± 5 | 116 ± 5 | 111 ± 8 | 122 ± 8 | 119 ± 5 | 115 ± 8 |
| RV end-diastolic pressure, mmHg | 4.50 ± 0.72 | 3.65 ± 0.38 | 3.00 ± 0.44 | 6.48 ± 0.71 | 6.46 ± 1.28* | 4.46 ± 0.84 |
| RV end-systolic volume index, μL/g | 0.26 ± 0.03 | 0.25 ± 0.04 | 0.24 ± 0.05 | 0.54 ± 0.04* | 0.49 ± 0.09* | 0.32 ± 0.07 |
| RV end-diastolic volume index, μL/g | 0.94 ± 0.06 | 0.99 ± 0.11 | 0.71 ± 0.09 | 1.04 ± 0.06 | 1.14 ± 0.11 | 0.61 ± 0.08†‡ |
Values are presented as means ± SE. PAB, pulmonary artery banding; RV, right ventricle; Sham, sham surgery. n = 8–10 animals per group. P < 0.05 for *PAB vs. respective Sham, †female [intact or ovariectomized (OVX)] vs. male, and ‡OVX vs. intact female (2-way ANOVA with Tukey’s honestly significant difference multiple comparison correction).