Table 2.
The GO terms analysis for DEGs between IUGR and AGA.
| Term | Description | P-value | N | Genes |
|---|---|---|---|---|
| (A) TOP 10 GO TERMS FOR THE BIOLOGICAL PROCESS | ||||
| GO:0044281 | Small molecule metabolic process | 6.62E-15 | 59 | Ehhadh, Hao1, Elovl5, Galm, Rgn, Gucy2c, Gldc, Oat, acl1, Abhd1…… |
| GO:0006631 | Fatty acid metabolic process | 5.11E-09 | 21 | Ehhadh, Hao1, Elovl5, Hacl1, Abhd1, Acsm5, Acot5, Acot4, Acot3, Fabp1…… |
| GO:0032787 | Monocarboxylic acid metabolic process | 5.53E-09 | 26 | Ehhadh, Hao1, Elovl5, Hacl1, Abhd1, Acsm5, Acot5, Acot4, Acot3, Fabp1…… |
| GO:0006629 | Lipid metabolic process | 5.60E-09 | 39 | Ehhadh, Hao1, Elovl5, Nrih4, Pnpla2, Hacl1, Agmo, Abhd1, Acsm5, Acot5 …… |
| GO:0006082 | Organic acid metabolic process | 7.90E-09 | 34 | Ehhadh, Hao1, Elovl5, Rgn, Gldc, Oat, Hacl1, Abhd1, Acsm5, Acot5 …… |
| GO:0019752 | Carboxylic acid metabolic process | 7.90E-09 | 33 | Ehhadh, Hao1, Elovl5, Rgn, Gldc, Oat, Hacl1, Abhd1, Acsm5, Acot5 …… |
| GO:0043436 | Oxoacid metabolic process | 1.70E-08 | 33 | Ehhadh, Hao1, Elovl5, Rgn, Gldc, Oat, Hacl1, Abhd1, Acsm5, Acot5 …… |
| GO:0051186 | Cofactor metabolic process | 1.51E-07 | 23 | Rgn, Hbe1, Hbg1, Acsm5, Acot5, Acot4, Acot3, Gpd1, Elovl5, Aldh1l2…… |
| GO:0015936 | Coenzyme metabolic process | 1.30E-06 | 18 | Rgn, Acsm5, Acot5, Acot4, Acot3, Gpd1, Elovl5, Aldh1l2 Acot2, Pank1…… |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | 1.73E-06 | 25 | Gucy2c, Acsm5, Acot5, Acot4, Acot3, Dpys, Nt5c3a, Gpd1, Ppargc1a, Upp2…… |
| (B) TOP 10 GO TERMS FOR THE MF | ||||
| GO:0008514 | Organic anion transmembrane transporter activity | 1.96E-06 | 14 | Slc25a32, Slc7a2, Slc13a4, Slc25a15, Slc17a2, Slc17a4, Ctns, Slc25a42, Slc25a23, Slc2a1…… |
| GO:0008509 | Anion transmembrane transporter activity | 7.52E-06 | 16 | Slc25a32, Slc7a2, Slc13a4, Slc25a15, Slc17a2, Slc17a4, Ttyh2, Ctns, Slco1b2, Slc25a23…… |
| GO:0015171 | Amino acid transmembrane transporter activity | 8.63E-06 | 8 | Ctns, Slc7a11, Slc16a10, Slc38a2, Slc7a2, Slc25a15, Slc7a1, Slc25a29 |
| GO:0005342 | Organic acid transmembrane transporter activity | 1.06E-05 | 11 | Slc25a32, Slc7a2, Slc13a4, Slc25a15, Slc17a2, Slc17a4, Ctns, Slco1b2, Slc26a1, Slc16a10…… |
| GO:0046943 | Carboxylic acid transmembrane transporter activity | 1.06E-05 | 11 | Slc25a32, Slc7a2, Slc13a4, Slc25a15, Slc17a2, Slc17a4, Ctns, Slco1b2, Slc26a1, Slc16a10…… |
| GO:0015179 | L-amino acid transmembrane transporter activity | 1.21E-05 | 7 | Ctns, Slc7a11, Slc38a2, Slc7a2, Slc25a15, Slc7a1, Slc25a29 |
| GO:0031625 | Ubiquitin protein ligase binding | 2.68E-05 | 15 | Gabarapl1, Fzd5, Erbb2, Per1, Ppargc1a, Cdkn1a, Map1lc3b, Cbs, Myc, Usp2…… |
| GO:0044389 | Ubiquitin-like protein ligase binding | 4.65E-05 | 15 | Gabarapl1, Fzd5, Erbb2, Per1, Ppargc1a, Cdkn1a, Map1lc3b, Cbs, Myc, Usp2…… |
| GO:0048037 | Cofactor binding | 6.40E-05 | 20 | Hao1, Gldc, Oat, Hacl1, Hbe1, Hbg1, Gpd1, Gstm2, Maob, Fmo3…… |
| GO:0020037 | Heme binding | 1.03E-04 | 10 | Hbe1, Nr1d1, Cyp2c13, Hbg1, Cyp3a9, Cbs, Hbz, Cyp2j10, Cyp2c22, Cyp21a1 |
| (C) Top 4 GO terms for the CC | ||||
| GO:0005777 | Peroxisome | 3.52E-05 | 10 | Ehhadh, Hao1, rat, Hacl1, Acot4, Fabp1, Acsl1, Pxmp4, Hsdl2, Amacr |
| GO:0042579 | Microbody | 3.52E-05 | 10 | Ehhadh, Hao1, rat, Hacl1, Acot4, Fabp1, Acsl1, Pxmp4, Hsdl2, Amacr |
| GO:0009331 | Glycerol-3-phosphate dehydrogenase complex | 2.20E-02 | 2 | Gpd2, Gpd1 |
| GO:0005811 | Lipid droplet | 2.71E-02 | 5 | Cidec, Pnpla2, Plin2, Hsd3b7, Nsdhl |