Table 3.
The core pathways analysis for DEGs between IUGR and AGA.
| Term | KEGG pathway | P-value | N | Genes |
|---|---|---|---|---|
| rno03320 | PPAR signaling pathway | 9.00E-06 | 19 | Aqp7, Gk, Rxrg, Fabp1, Fabp2, Fabp4, Fabp7, Slc27a5, Angptl4, Plin2…… |
| rno04068 | FoxO signaling pathway | 2.43E-04 | 9 | Cdkn1a, Egfr, Egf, Il10, Sgk1, Gadd45b, Gabarapl1, Prkaa2, Bnip3 |
| rno04140 | Autophagy—animal | 3.95E-04 | 9 | Ddit4, Bcl2l1, Dapk1, Uvrag, Rb1cc1, Prap1, Gabarapl1, Prkaa2, Bnip3 |
| rno04012 | ErbB signaling pathway | 4.58E-04 | 7 | Nrg1, Cdkn1a, Cblb, Egfr, Erbb2, Myc, Egf |
| rno00591 | Linoleic acid metabolism | 4.84E-04 | 5 | Cyp3a9, Cyp2c22, Cyp2c13, Cyp2j10, Pla2g12a |
| rno04920 | Adipocytokine signaling pathway | 1.06E-03 | 7 | Acsl4, Npy, Slc2a1, Nfkbia, Prkaa2, Ppargc1a, rxrg |
| rno04066 | HIF-1 signaling pathway | 2.33E-03 | 7 | Cdkn1a, Ifngr1, Pfkfb3, Egfr, Erbb2, Slc2a1, Egf |
| rno04630 | JAK-STAT signaling pathway | 3.08E-03 | 8 | Cdkn1a, Ifngr1, Egfr, Myc, Bcl2l1, Il6st, Egf, Il10 |
| rno04060 | Cytokine–cytokine receptor interaction | 3.45E-03 | 11 | Cxcl2, Ifngr1, Il1r2, Il6st, Il10, Il18, Tnfrsf12a, Il17rb, Relt, Il1rn…… |
| rno04922 | Glucagon signaling pathway | 4.50E-03 | 8 | Sik1, Ppargc1a, Prkaa2, Pde3b, Slc2a1, Fbp1, Ldha, Gcgr |