Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 7;13:858256. doi: 10.3389/fimmu.2022.858256

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Lu, Sun, Xu, Saaoud, Shao, Drummer, Wu, Hu, Yu, Kunapuli, Bethea, Vazquez-Padron, Sun, Jiang, Wang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Ang-II induced AAA, canonical, caspase 4, and exosome SGs in aortas have two expression peaks of high (Day 7)-low (Day 14)-high (Day 28) patterns suggesting the evidence of trained immunity response. (A) Canonical, caspase 4-GSDMD, and exosome pathways have two peak (three-phase) of high (Day 7)-low (Day 14)-high (Day 28) patterns; and caspase 1-GSDMD, Weibel-Palade body, and autophagy secretomes are only functional at the Day 7 AAA aortas. P < 0.05, LogFC>1 or < -1. (B) The signal pathways of secretomic genes are different in AAA progression. Z score>1.