Figure 2.

Forest plot demonstrating composite of heart failure hospitalization or cardiovascular death between patients on SGLT2 inhibitors vs. placebo/control in randomized controlled trials stratified by (A) LVEF at baseline and (B) DM status at baseline. Square markers represent point estimate of HR for individual studies, with square size representing proportional weight given to each study in the meta‐analysis. Horizontal lines indicate 95% CIs. The solid diamonds represent the estimated 95% CI for effect size of all meta‐analysed data. Abbreviations: CI, confidence interval; CV, cardiovascular; DM, diabetes mellitus; EF, ejection fraction; HFH, heart failure hospitalization; HR, hazard ratio; RR, risk ratio; SGLT, sodium glucose cotransporter.