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. 2022 Mar 7;10:835733. doi: 10.3389/fchem.2022.835733

TABLE 2.

Dissociation constants of dimerization determined for 14-3-3ζ variants. Populations of monomers and dimers at 25 μM concentrations are included.

14-3-3 KD (M) (%) (D) (%)
ζ_S58E (0.35 ± 0.25) μM 8.02 91.98
ζ_S58D (132 ± 7) μM 77.34 22.66
ζ_S57D_S58D (348 ± 19) μM 88.70 11.30
ζm (4.6 ± 0.1) mM 98.94 1.06
(7.6 ± 0.8) mM 99.35 0.65