Fig. 1.
Tissue-specific signatures in the mid-gestation placenta. (A) Diagram of placental tissues. (B) Hematoxylin & Eosin staining of placental tissues (n=19). (C) All differentially expressed genes between placental tissues with P<0.05, false-discovery rate<20% and fold change>absolute value 2 (n=3). (D) CD45pos CD163lo/neg cells within the intravillous space identified with immunofluorescence (n=19). (E) Top: Fluorescence in situ hybridization of Y chromosome in PV. Bottom: Delta CT values of Y (left) and X (right) chromosome genes in male and female PV (n=1 male, 1 female). (F) Expression values of selected immune genes. Circle size indicates expression value. Circle color indicates relative expression across row. n=3 per tissue type. DE, differentially expressed. Graphs show mean±s.e.m.