Figure 1.

Lipidomics analysis of the lipids whose abundance was significantly changed in clinical PM-CRC specimens. A, Schematic of the lipidomics analysis of primary tumors from patients with nonperitoneal metastatic colorectal cancer (Non-PM, n=22) or peritoneal metastatic colorectal cancer (PM, n=23). B, Altered lipids are displayed as clusters in the heat map. C, Relative intensity of lipid species whose abundance was significantly changed. D, Lipid composition influences physical membrane properties. E, Distributions of phosphatidylcholine (PC) with two hydrophobic acyl chains within different lipid classes in the clinical CRC specimens. Bars, mean ± SD. *p < 0.05, **p < 0.01.