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. 2022 Feb 21;18(5):2003–2017. doi: 10.7150/ijbs.69618

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Aristolochic acid targeting proteins participate in key metabolic processes in kidney. (A) Volcano plot depicting the differential enrichment of proteins in AP2 (probe) vs DMSO groups. (B) Temporal patterns for AA targeting proteins (AP2 vs DMSO). (C) Venn digraph depicting the same target proteins of AA in kidney tissues and HK-2 cells. (D) Target proteins involved in essential biological processes by Gene Ontology (GO) analysis. (E) The representative AA targets and their biological functions.