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. 2022 Feb 21;18(5):1878–1895. doi: 10.7150/ijbs.69934

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HSPA5 expression is associated with autophagy in nasopharyngeal carcinoma. (A) Western blot experiment detected autophagy in NPC cell lines. (B, C) GFP-LC3 transfection was used to detect autophagosomes. (D, E) Colony formation demonstrated that autophagy inhibitors modulated radiosensitivity of NPC. (F) Immunohistochemical experiments showed that the expression of LC3B and HSPA5 in NPC tissues. (G) Cell immunofluorescence showed the expression of HSPA5 and LC3B. (H) Immunofluorescence showed that the expressions of HSPA5 and LC3B in tumor tissues.