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. 2022 Feb 14;18(5):1829–1843. doi: 10.7150/ijbs.66917

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Fig 1 — The molecular mechanism of ferroptosis. Cys₂: Cysteine; Glu: Glutamate; SLC7A11: Solute carrier family 7 membrane 11; SLC3A2: Solute carrier family 3 membrane 2; SLC40A1: Solute carrier family 40 membrane 1; TFRC: Transferrin receptor; GSH: Reduced glutathione; GPX4: Glutathione peroxidase 4; GSR: Glutathione reductase; GSSG: Oxidized Glutathione; ROS: Reactive oxygen species; AA: Arachidonic acid; ACSL4: Acyl-CoA synthetase long-chain family member 4; LPCAT3: lysophophatidylcholne acyltransferase 3; ALOXs: Lipoxygenases