Table 1.

The regulatory role of ncRNAs in cancer progression via ferroptosis of cancer cells.

Cancers	NcRNAs	Mechanism	Function	Reference
Lung cancer	exo-miR-4443	Target METTL3/FSP1	Induce ferroptosis and increase cisplatin resistance of NSCLC	67
	miR-324-3p	Target GPX	Induce ferroptosis and reduce cisplatin resistance	88
	miR-27a-3p	Target SLC7A11	Induce ferroptosis and inhibit lung cancer	86
	lncRNA P53RRA	Interact with G3BP1	Induce ferroptosis and inhibit lung cancer	77
	LINC00336	Sponge with miR-6825 as ceRNA	Inhibit ferroptosis and promoting lung cancer	82
	lncRNA mir503HG	Sponge with miR-1273c as ceRNA	Induce ferroptosis and inhibit NCSLC	103
	lncRNA NEAT1	Upregulate the expression of ACSL4	Induce ferroptosis and inhibit NCSLC	96
	lncRNA MT1DP	target miR-365a-3p/NRF2	Induce ferroptosis and inhibit NCSLC	72
	lncRNA ASMTL-AS1	Stabilzing SAT1 and recruiting U2AF2	Induce ferroptosis and inhibit NCSLC	104
	circDTL	Target miR-1287-5p/GPX4	Inhibit ferroptosis and promote lung cancer	108
Gastrointestinal cancer	miR-4715-3p	DNA methylation and downregulate AURKA	Induce ferroptosis and inhibit UGC	75
	exo-miR-522	Interact with ALOX15	Inhibit ferroptosis and promote chemotherapeutic resistance of GC	80
	miR-103a-3p	Target GLS2	Induce ferroptosis and inhibit GC	94
	miR-139-5p	Target SLC7A11	Induce ferroptosis and inhibit pancreatic carcinoma	109
	miR-375	Target SLC7A11	Induce ferroptosis and inhibit GC	110
	circ_0008035	Target miR-599/EIF4A1	Inhibit ferroptosis and promote GC	68
	circABCB10	Target miR-326/CCL5	Induce ferroptosis and inhibit rectal cancer	71
	circ_0007142	Target miR-874-3p/GDPD5	Induce ferroptosis and inhibit CRC	70
Liver cancer	miR-214-3p	Target ATF4	Induce ferroptosis and inhibit HCC	74
	lncRNA GABPB1-AS1	Downregulation of GABPB1 and PRDX5	Induce ferroptosis and inhibit HCC	69
	lncRNA PVT1	Target miR-214-3p/GPX4	Inhibit ferroptosis and promote liver cancer	90
	circIL4R	Target miR-541-3p/GPX4	Inhibit ferroptosis and promote HCC	91
	circcIARS	Target ALKBH5	Induce ferroptosis and inhibit HCC after SF treatment	126
	circ_0097009	Target miR-1261/SLC7A11	Inhibit ferroptosis and promote HCC	84
Breast cancer	miR-324-3p	Target GPX4	Induce ferroptosis and inhibit breast cancer	89
	miR-5096	Target SLC7A11	Induce ferroptosis and inhibit breast cancer	127
	lncRNA P53RRA	Interact with G3BP1	Induce ferroptosis and inhibit breast cancer	77
	circGFRA1	Target miR-1228/AIFM2	Inhibit ferroptosis and promote breast cancer	130
	circRHOT1	Target miR-106a-5p/STAT3	Inhibit ferroptosis and promote breast cancer	73
Urogenital cancer	lncRNA RP11-89	Target miR-129-5p/PROM2	Inhibit ferroptosis and promote urogenital cancer	132
Prostate cancer	lncRNA OIP5-AS1	Target miR-128-3p/SLC7A11	Inhibit ferroptosis and promote prostate cancer	135
Cervical cancer	circEPSTI1	Target miR-375/409-3P/515-5p/SLC7A11	Inhibit ferroptosis and promote cervical cancer	85
Ovarian cancer	miR-424-5p	Target ACSL4	Inhibit ferroptosis and promote ovarian cancer	97
Acute myeloid leukemia	LINC00618	Downregulate SLC7A11	Induce ferroptosis and inhibit Acute myeloid leukemia	79
Glioma	miR-18a	Downregulate ALOXE3	Inhibit ferroptosis and promote glioma	98
	circTTBK2	Target miR-761/ITGB8	Inhibit ferroptosis and promote glioma	76
Head and neck squamous cell carcinoma	miR-125b-5p	Target SLC7A11	Inhibit ferroptosis and promote tongue squamous cell carcinoma	87
	circFNDC3B	Target miR-520d-5p/SLC7A11	Inhibit ferroptosis and promote orall squamous cell carcinoma	78
	circKIF4A	Target miR-1231/GPX4	Inhibit ferroptosis and promote papillary thyroid cancer	92
	circ_0067934	Target miR-545-3p/SLC7A11	Inhibit ferroptosis and promote thyroid cancer	144
Melanoma	miR-137	Downregulate SLC1A5	Induce ferroptosis and inhibit melanoma	81
	miR-9	Downregulate GOT1	inhibit ferroptosis and promote melanoma	95
Clinically relevant radioresistance	miR-7-5p	-	Inhibit ferroptosis and promote CRR	83