Table 2.

Univariate and multivariate analysis of clinicopathologic factors for OS and RFS

Univariate analysis
Variables	OS		RFS
	HR (95.0% CI)	P	HR (95.0% CI)	P
Age(years)	0.899 (0.642-1.260)	0.538	1.082(0.771-1.519)	0.648
Tumor size	1.170(0.794-1.723)	0.428	1.287(0.875-1.893)	0.200
LN metastasis	1.663(1.403-1.970)	0.000a	1.548(1.300-1.843)	0.000a
Histological grade	1.656(1.268-2.161)	0.000a	1.427(1.097-1.857)	0.008a
Pathologic types	1.016(0.721-1.432)	0.928	0.934(0.663-1.315)	0.696
SENP1	2.771(1.882-4.079)	0.000a	2.319(1.471-3.110)	0.000a
Multivariate analysis
LN metastasis	1.566(1.311-1.871)	0.000a	1.467(1.221-1.763)	0.001a
Histological grade	1.338(1.005-1.780)	0.046	1.149(0.870-1.517)	0.326
SENP1	2.552(1.724-3.778)	0.000a	1.933(1.317-2.836)	0.000a

Abbreviation: LN, lymph node; OS, overall survival; RFS, relapse-free survival

aStatistically significant (P < 0.05)