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. Author manuscript; available in PMC: 2022 Mar 21.
Published in final edited form as: Nature. 2021 Jun 28;596(7870):109–113. doi: 10.1038/s41586-021-03738-2

Fig. 2|. Germinal centre B cell response to SARS-CoV-2 immunization.

Fig. 2|

a, Representative colour Doppler ultrasound image of two draining lymph nodes (‘1’ and ‘2’) adjacent to the axillary vein ‘LAX V’ 5 weeks after immunization. b, c, Representative flow cytometry plots of BCL6 and CD38 staining on IgDlowCD19+CD3− live singlet lymphocytes in FNA samples (b; LN1, top row; LN2, bottom row) and S staining on BCL6+CD38int germinal centre B cells in tonsil and FNA samples (c) at the indicated times after immunization. d, e, Kinetics of total (blue) and S+ (white) germinal centre (GC) B cells as gated in b and c (d) and S-binding per cent of germinal centre B cells (e) from FNA of draining lymph nodes. Symbols at each time point represent one FNA sample; square symbols denote the second lymph node sampled (n = 14). Horizontal lines indicate the median.