Figure 3. Joint Effects of All Cortical and Subcortical GM Regions and WM Tracts.

(A) Acute stroke severity (NIH Stroke Scale [NIHSS] score). The posterior distribution of the hyperprior capturing the effect of all subcortical gray matter (GM) regions did not substantially overlap with zero (i.e., the highest probability density interval covering 90% certainty did not include the zero, highlighted by the red frame). (B) Ninety-day unfavorable outcome (modified Rankin Scale score >2). Conversely, the contribution of white matter (WM) tract lesions was the most meaningful for long-term outcomes, while posterior distributions for GM lesion hyperpriors did not substantially differ from zero.