Figure 1. CHANCE^NMO-Study Cohort Categorized by Serostatus, EDSS Score, and Disease Duration.

Age and disease duration are shown as median with range in years; female sex and serostatus (aquaporin-4 [AQP4]/neg/ myelin oligodendrocyte glycoprotein [MOG]) are shown as percentage. Patient subgroups were defined on the basis of serostatus, clinical disability (Expanded Disability Status Scale [EDSS] score [score is shown as median with range]), and disease duration. Category boundaries are shown above. EDSS scores for 8 patients were missing. In 1 patient, disease duration is unknown. In both cases, this had no effect on the representativeness of the group composition. IPND = International Panel for NMO Diagnosis; MOG(AD) = MOG immunoglobulin G (IgG) antibody (associated disease); neg = patients with AQP4 and MOG-antibody–negative NMOSD; NMOSD = neuromyelitis optica spectrum disorders.