Figure 3. Level of Problems Experienced by Patients Stratified by Disease Severity (A) and Serostatus (B).
Patients were able to provide levels on a scale from 0 to 5 (0 = no problems, 5 = unable/ extreme problems) for each of the 5 dimensions of the EuroQoL 5 Dimensions 5 Levels questionnaire. Pain/discomfort between the aquaporin-4 (AQP4) immunoglobulin G (IgG) antibody–positive neuromyelitis optica spectrum disorder (NMOSD) group and the double seronegative NMOSD group was the only dimension that differed significantly (p = 0.009). EDSS = Expanded Disability Status Scale; IPND = International Panel for NMO Diagnosis; MOGAD = myelin oligodendrocyte glycoprotein IgG antibody–positive disease.