Fig. 3.

In vitro inhibition of D. typus crude venom SVMP activity by small molecule inhibitors. A) SVMP activity of D. typus crude venom in the presence of marimastat (teal circles), prinomastat (dark purple circles), dimercaprol (black circles) and DMPS (pink circles) over a two-fold serial dilution curve, from which IC₅₀ values were calculated. Data points represent the percentage of crude venom SVMP activity generated from the mean of four individual values recorded over two independent technical replicates, and error bars represent standard deviation. B) IC₅₀ values of SVMP inhibition for marimastat, prinomastat, dimercaprol and DMPS.