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. 2022 Mar 21;22:147. doi: 10.1186/s12887-022-03213-5

Table 4.

Multilevel multivariate logistics regression models to identify the predisposing factors that affected children between 0 and 23 months old living in South Sudan from being on track with their routine immunisation schedule

Variable Crude Estimate Model 1a Model 2b Model 3c
cOR (CI) aOR (CI) aOR (CI) aOR (CI)
Individual-level factors
Maternal and Child Characteristics
  Parity
   1 child 1 (reference) 1 (reference) 1 (reference) 1 (reference)
   2–5 children 0.82 (0.40, 1.68) 0.55 (0.23, 1.28)# 0.58 (0.18, 1.85)# 1.01 (0.45, 2.23)#
   6 and above 0.43 (0.19, 0.93) 0.28 (0.09, 0.83) 0.32 (0.08, 1.12)# 0.40 (0.16, 0.96)
Community Characteristics
  Immunization benefits
   Protection against diseases 1 (reference) 1 (reference) 1 (reference) 1 (reference)
   Child Growth 3.96 (1.35,11.53) 5.94 (1.70, 20.71) 23.05 (2.81,188.68) 7.45 (2.06, 26.87)
  Churches discussed immunization importance
   Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
   No 7.42 (4.28,12.82) 5.75 (2.79, 11.80) 1.62 (0.60, 4.37)# 7.62 (3.90, 14.87)
  Community discussed immunization importance
   Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 7.76 (4.50,13.36) 5.62 (2.6, 11.86) 1.77 (0.58, 5.34)# 8.01 (4.02, 15.92)
State (health system) related factors
Frequent provision of immunization at health facility on daily bases
  Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 1.80 (1.11, 2.90) 1.93 (1.04, 3.57) 1.59 (0.80, 3.14)# 1.01 (0.53, 1.89)#
Vaccinator conduct outreach immunization
  Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 2.32 (1.45,3.71) 2.27 (1.29, 3.98) 4.12 (1.91, 8.88) 7.21 (3.82, 13.5)
Vaccinator visit during family livelihood business
  Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 0.40 (0.21,0.68) 0.56 (0.29,1.09) 0.32 (0.13, 0.73) 0.43 (0.23, 0.80)
Health facility too far and no transportation to going for immunization
  Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 0.20 (0.10,0.37) 0.26 (0.12, 0.54) 0.19 (0.07, 0.48) 0.17 (0.08, 0.35)
Inadequate notice about immunization outreach visit to community
  Yes 1 (reference) 1 (reference) 1 (reference) 1 (reference)
  No 0.23 (0.12, 0.42) 0.15 (0.05, 0.39) 0.39 (0.16, 0.91) 0.68 (0.29, 1.55)#
Multivariable logistic regression models to control for them using forward selection stepwise regression
Crude Estimates Adjusted Estimates
Variables Crude Odd Ratio (95% CI) P -value Adj Odd Ratio (95% CI) P -value
Immunization benefits: Association:
 Immunisation benefit adjusted for Frequent provision of immunization at health facility on daily bases 3.96 (1.35,11.53) 0.012 3.53 (1.199, 10.36) 0.022
 Immunisation benefit adjusted for (Frequent provision of immunization at health facility on daily bases + Maternal Age (25–34 years)) 3.36 (1.12, 10.05) 0.03
 Immunisation benefit adjusted for (Frequent provision of immunization at health facility on daily bases + Maternal Age (25–34 years) + Health facility too far and no transportation to going for immunization) 4.34 (1.23, 15.24) 0.022
vaccinator conduct outreach immunization
 vaccinator conduct outreach immunization adjusted for immunisation benefit 2.32 (1.45,3.71) < 0.001 2.05 (1.24, 3.39) 0.005
 vaccinator conduct outreach immunization adjusted for (immunisation benefit + Maternal age (25–34 years old)) 2.18 (1.25, 3.78) 0.005
 vaccinator conduct outreach immunization adjusted for (immunisation benefit + Maternal age (25–34 years old) + Vaccinator visit during family livelihood business) 2.27 (1.29, 3.96) 0.004
 vaccinator conduct outreach immunization adjusted for (immunisation benefit + Maternal age (25–34 years old) + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back) 2.26 (1.29, 3.94) 0.004
 vaccinator conduct outreach immunization adjusted for (immunisation benefit + Maternal age (25–34 years old) + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back + Health facility too far and no transportation to going for immunization) 1.81 (1.00, 3.25) 0.046
Vaccinator visit during family livelihood business:
 Vaccinator visit during family livelihood business adjusted for Availability of children immunization card 0.40 (0.21,0.68) 0.001 0.35 (0.19, 0.64) 0.001
 Vaccinator visit during family livelihood business adjusted for Availability of children immunization card + Functional facility type in the area) 0.32 (0.17, 0.59) < 0.001
 Vaccinator visit during family livelihood business adjusted for Availability of children immunization card + Functional facility type in the area + Health facility conduct routine immunization outreach services 0.33 (0.17, 0.62) 0.001
Health facility too far and no transportation to going for immunization:
 Health facility too far and no transportation to going for immunization adjusted for Functional facility type in the area 0.20 (0.10,0.37) < 0.001 0.14 (0.07, 0 .26) < 0.001
 Health facility too far and no transportation to going for immunization adjusted for Functional facility type in the area + Inadequate notice about immunization outreach visit to community) 0.15 (0.07, 0.28) < 0.001
Inadequate notice about immunization outreach visit to community:
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age 0.23 (0.12, 0.42) < 0.001 0.11 (0.04, 0.28) < 0.001
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age + vaccinator conduct outreach immunisation 0.10 (0.03, 0.25) < 0.001
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age + vaccinator conduct outreach immunisation + Parity (above 6 children) 0.10 (0.03, 0.25) < 0.001
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age + vaccinator conduct outreach immunisation + Parity (above 6 children) + Health facility too far and no transportation to going for immunization 0.11 (0.04, 0.27) < 0.001
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age + vaccinator conduct outreach immunisation + Parity (above 6 children) + Health facility too far and no transportation to going for immunization +child card availability 0.12 (0.04, 0.31) < 0.001
 Inadequate notice about immunization outreach visit to community adjusted for Maternal Age + vaccinator conduct outreach immunisation + Parity (above 6 children) + Health facility too far and no transportation to going for immunization +child card availability +Vaccinator not happy for coming regularly to the community 0.14 (0.05, 0.37) < 0.001
Churches discussed immunization importance:
 Churches discussed immunization importance adjusted for county 7.42 (4.28,12.82) < 0.001 2.42 (1.16, 5.01) 0.018
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation 1.95 (0.92, 4.13) 0.081
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian 2.02 (0.87, 4.65) 0.099
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business 1.82 (0.77, 4.24) 0.169
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back 1.77 (0.75, 4.18) 0.191
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back + Functional facility type in the area 1.93 (0.80, 4.63) 0.139
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Availability of children immunization card 2.19 (0.87, 5.47) 0.094
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Availability of children immunization card + Frequent provision of immunisation at health facility 2.26 (0.89, 5.72) 0.085
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Availability of children immunization card + Frequent provision of immunisation at health facility + Inadequate notice about immunization outreach visit to community 2.19 (0.82, 5.82) 0.115
 Churches discussed immunization importance adjusted for county + Health facility too far and no transportation to go for immunisation + Are you parent or guardian + Vaccinator visit during family livelihood business + Availability of children immunization card + Frequent provision of immunisation at health facility + Inadequate notice about immunization outreach visit to community + Health Facility conduct routine immunisation outreach 2.09 (0.78, 5.59) 0.141
Community discussed immunization importance:
 Community discussed immunization importance: adjusted for Churches discussed immunization importance 7.76 (4.50,13.36) < 0.001 3.62 (1.42, 9.18) 0.007
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card 2.22 (0.85, 5.80) 0.103
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization 2.22 (0.85, 5.74) 0.099
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child 1.94 (0.74, 5.07) 0.178
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types 1.38 (0.47, 3.97) 0.551
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community 1.13 (0.36, 3.43) 0.836
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community + Vaccinator visit during family livelihood business 1.13 (0.37, 3.364) 0.829
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back 1.23 (0.40, 3.71) 0.711
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back + Parity (above 6 children) 1.18 (0.38, 3.59) 0.777
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back + Parity (above 6 children) + Frequent provision of immunisation at health facility 1.24 (0.39, 3.84) 0.713
 Community discussed immunization importance: adjusted for Churches discussed immunization importance + Availability of children immunization card + Health facility too far and no transportation to going for immunization + Are you Parent/guardian of the child + Functional health facility types + Inadequate notice about immunization outreach visit to community + Vaccinator visit during family livelihood business + Not completed all the immunization for my child, not informed to come back + Parity (above 6 children) + Frequent provision of immunisation at health facility + Health facility conduct routine immunisation outreaches 1.29 (0.40, 4.05) 0.665

Model 1: Association is adjusted for Maternal Age + parity + parent/guardian + child availability card

Model 2: Association is adjusted for immunisation benefit + community discussed + church discussed + Vaccinator visit during family livelihood business + BHWs + Health facility too far and no transportation to go for immunization

Model 3: Association is adjusted for Functional facility type in the area + Health facility conduct routine immunization outreach services + vaccinator not happy + did not inform to come back + frequent provision of immunisation at the health facilities + inadequate notice + health facility conduct routine immunisation

#means it is not statistically significant (p value > 0.05)