Table 2.
Histopathology.
| Patie nt No. |
Prior Diagnosis |
Renal Neoplasm | Size (cm) |
Other Features | Grade (WHO/ISUP) |
pT | N | M |
|---|---|---|---|---|---|---|---|---|
| 1 | Wilms Tumor (R) | Clear Cell RCC (L) | 5.2 | Rhabdoid+, Sarcomatoid+, Necrosis+ | 4 | pT3a | NX | MX |
| 2 | Wilms Tumor (R) | Clear Cell RCC (L) | 6.6 | Rhabdoid+, Necrosis+ | 4 | pT1b | NX | MX |
| 3 | Wilms Tumor (R) | Tumor1: Clear Cell RCC (L) | 5.0 | - | 2 | pT1b | NX | MX |
| Tumor2: Oncocytoma (L) | 2.5 | (Synchronous) | NA | NA | NA | NA | ||
| 4 | Wilms Tumor (L) | Clear Cell RCC (R) | 8.5 | Rhabdoid+, Necrosis+ | 4 | pT3a | NX | MX |
| 5 | Wilms Tumor (R) | Metanephric Adenoma (L) | 1.2 | - | NA | NA | NX | MX |
| 6 | Wilms Tumor (R) | Tumor1 (L): Metanephric Adenoma | 1.2 | - | NA | NA | NX | MX |
| Tumor2 (L): Oncocytoma | 1.5 | (Synchronous) | NA | NA | NA | NA | ||
| Tumor3 (L): Metanephric Adenoma | 2.3* | (Metachronous; Biopsy/Cryoablation) | NA | NA | NA | NA | ||
| Tumor4 (L): Unknown | 2.1* | (Metachronous; Cryoablation) | NA | NA | NA | NA | ||
| 7 | Neuroblastoma (left) | t(6;11) RCC* (R) | 5.4 | - | 3 | pT1b | N0 | M0 |
| 8 | Neuroblastoma (right) | Clear Cell RCC (R) | 1.5 | - | 1 | pT1a | NX | MX |
| 9 | Neuroblastoma (right) | Clear Cell RCC (R) | 2.4 | - | 2 | pT1a | NX | MX |
| 10 | Neuroblastoma (left) | Clear Cell RCC (L) | 2.7 | Cystic | 1 | pT1a | NX | MX |
| 11 | Neuroblastoma (laterality unknown) | Clear Cell RCC (L) | 9.7 | - | 2 | pT2a | NX | MX |
| 12 | ALL | FH-Deficient RCC (L) | 13.5 | LVI+, (3/7 lymph nodes+), adrenal metastasis+ | 3 | pT3a | N1 | M1 |
| 13 | ALL | Clear Cell RCC (R) | 12.5 | - | 2 | pT3a | NX | MX |
| 14 | SLE | Tumor1 (R): ASPL-TFE3** rearranged RCC2 | 8.0 | - | - | pT3a | NX | MX |
| Tumor2 (L): PRCC-TFE3** rearranged RCC | 5.0 | Associated with 14.0 cm retroperitoneal mass and involvement of 1 (of 2) perinephric lymph nodes | - | pT2a | N1 | M1 |
L: left kidney; R: right kidney; ALL: acute lymphoblastic leukemia; SLE: systemic lupus erythematosus; RCC: renal cell carcinoma; FH: fumarate hydratase; LVI: lymphovascular invasion; WHO: World Health Organization; ISUP: International Society of Urologic Pathology.
*
Patient 7 was reported previously by Gupta et al (2019)
**
Patient 14 was reported previously by Argani et al (2001 and 2006).