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. 2022 Mar 21;15:97. doi: 10.1186/s13071-022-05227-5

Table 1.

Mortality rate (%) of snails after wettable powder of niclosamide (WPN) treatment with or without the alternative oxidase (AOX) inhibitor salicylhydroxamic acid (SHAM)

Group 6 h 12 h 24 h 48 h χ2 P
H2O 5.00 ± 7.07 3.33 ± 2.36 1.67 ± 2.36 5.33 ± 4.11 0.247 0.684
Methanol 1.67 ± 2.36 7.22 ± 6.14 2.78 ± 2.08 12.50 ± 2.50 3.761 0.056
SHAM 6.67 ± 6.24 5.00 ± 4.08 1.67 ± 2.36 12.50 ± 2.50 0.751 0.415
0.04 mg/L WPN 0.00 ± 0.00 0.00 ± 0.00 1.25 ± 2.17 10.89 ± 11.69 a, b 14.656 0.000
0.06 mg/L WPN 1.25 ± 2.17 1.25 ± 2.17 8.75 ± 4.15 32.50 ± 10.90* a, b, c 40.815 0.000
0.08 mg/L WPN 2.50 ± 2.50 2.50 ± 2.50 18.57 ± 7.49* a, b 60.24 ± 13.12* a, b, c 88.298 0.000
0.1 mg/L WPN 5.24 ± 0.34 32.21 ± 12.66* a 49.58 ± 9.60* a 91.67 ± 8.03* a, b, c 144.024 0.000
0.04 mg/L WPN + SHAM 0.00 ± 0.00 3.67 ± 2.62 d 34.90 ± 3.74* a, b 91.72 ± 6.02* a, b, c 216.473 0.000
0.06 mg/L WPN + SHAM 2.50 ± 2.50 7.32 ± 4.02 d 77.50 ± 5.59* a, b, d 95.00 ± 3.54* a, b, c 194.708 0.000
0.08 mg/L WPN + SHAM 11.25 ± 4.15 34.29 ± 12.05* a 82.50 ± 5.59* a, b, d 100.00 ± 0.00* a, b, c, d 161.253 0.000
0.1 mg/L WPN + SHAM 19.29 ± 3.75* d 46.68 ± 6.74* ad 87.32 ± 9.17* a, b, d 100.00 ± 0.00* a, b, c, d 189.074 0.000

Lowercase letters indicate the following: a, mortality at that time point was significantly higher than that at 6 h for the same group (P < 0.05); b, mortality at that time point was significantly higher than that at 12 h for the same group (P < 0.05); c, mortality at that time point was significantly higher than that at 24 h, for the same group (P < 0.05); d, significant difference in mortality between the treatment group and the 0.1 WPN group at that time point (P < 0.05)

* P < 0.05 (significant difference in mortality between that treatment group and the H2O group at that time point)