Table 3.
Summary of clinical and demographic predictors of neuropsychological test performance
| ADAS-Cog | AVLT T1-T5 | AVLT T6 | AVLT DR | LM I | LM II | BNT | Fluency | TMT A | TMT B | |
|
| ||||||||||
| Model R2 | 0.21 | 0.28 | 0.21 | 0.18 | 0.30 | 0.30 | 0.01 | 0.13 | 0.08 | 0.19 |
| F-statistic | 13.07 | 18.26 | 12.66 | 10.46 | 20.23 | 20.23 | 1.61 | 7.65 | 5.08 | 11.66 |
| DF | 8, 346 | 8, 347 | 8, 345 | 8, 346 | 8, 346 | 8, 346 | 8, 347 | 8, 347 | 8, 347 | 8, 345 |
|
| ||||||||||
| β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | β (S.E.) | |
|
| ||||||||||
| Intercept | 9.05*** (0.52) | 45.95*** (1.06) | 9.19*** (0.38) | 8.05*** (0.44) | 14.11*** (0.36) | 12.93*** (0.38) | 28.18*** (0.33) | 20.27*** (0.58) | 3.50*** (0.04) | 4.30*** (0.04) |
| Age | 1.36*** (0.25) | −3.10*** (0.50) | −1.05*** (0.38) | −0.99*** (0.43) | −0.18 (0.17) | −0.06 (0.18) | −0.11 (0.16) | −0.77** (0.28) | 0.06*** (0.02) | 0.11*** (0.02) |
| Sex | −0.85 (0.52) | 3.85*** (1.04) | 0.92* (0.38) | 1.00* (0.43) | 0.29 (0.36) | 0.19 (0.38) | −0.44 (0.32) | 0.57 (0.57) | −0.08* (0.04) | −0.02 (0.04) |
| Education | −0.45 (0.25) | 1.31** (0.50) | 0.38* (0.18) | 0.50* (0.21) | 0.41* (0.17) | 0.35 (0.18) | 0.13 (0.16) | 1.03*** (0.27) | −0.01 (0.02) | −0.05** (0.02) |
| MMSE | −0.61* (0.25) | 1.85*** (0.51) | 0.53** (0.19) | 0.41 (0.21) | 0.54** (0.18) | 0.72 (0.19) | 0.12 (0.16) | 0.94*** (0.28) | −0.06** (0.02) | −0.07*** (0.02) |
| Aβ SUVR | 0.10 (0.26) | −0.04 (0.53) | 0.46 (0.55) | −0.19 (0.22) | −0.37* (0.18) | −0.50* (0.19) | −0.22 (0.16) | 0.11 (0.29) | 0.01 (0.02) | 0.05* (0.02) |
| APOE ε4 + | −0.23 (0.58) | −2.06 (1.16) | −0.26 (0.42) | −0.75 (0.48) | −0.92* (0.40) | −0.26 (0.42) | −0.06 (0.36) | 0.84 (0.64) | −0.03 (0.04) | −0.002 (0.05) |
| MCI dx | 3.54*** (0.53) | −5.67*** (1.07) | −1.82*** (0.39) | −2.10*** (0.44) | −3.54*** (0.37) | −4.34*** (0.39) | −0.80* (0.33) | −1.57** (0.59) | 0.03 (0.04) | 0.12** (0.04) |
| LLD dx | 0.03 (0.51) | −4.20*** (1.03) | −1.09** (0.38) | −0.92* (0.43) | −0.04 (0.36) | −0.31 (0.37) | −0.16 (0.32) | 0.50 (0.57) | 0.04 (0.04) | 0.09* (0.04) |
ADAS, Alzheimer’s Disease Assessment Scale; AVLT, Auditory Verbal Learning Test; LM, Logical Memory; BNT, Boston Naming Test; TMT, Trail Making Test; DL, degrees of freedom
*
p < 0.05
**
p < 0.01
***
p < 0.001.