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. 2022 Mar 15;8(2):e71. doi: 10.1192/bjo.2022.37

Table 2.

Association between poverty in adolescence and drug use disorder in young adulthood. Results from Cox regression analysis with four-way decomposition by presence of adolescent psychiatric diagnosis

Drug use disorder in young adulthood (19–31 years of age)
Female Male
Estimate (95% CI) Estimate (95% CI)
Four-way decomposition by presence of psychiatric diagnosis in adolescence Model 1 Model 2 Model 1 Model 2
Total effects
Total excess relative risk (tereria) 0.54 (0.45–0.63) 0.40 (0.32–0.63) 0.60 (0.53–0.67) 0.43 (0.37–0.49)
Excess relative risk due to neither mediation nor interaction (ereri_cdea) 0.37 (0.29–0.44) 0.31 (0.23–0.45) 0.50 (0.44–0.56) 0.38 (0.31–0.43)
Excess relative risk due to interaction only (ereri_intrefa) 0.09 (0.05–0.14) 0.05 (0.02–0.13) 0.05 (0.02–0.07) 0.03 (0.01–0.04)
Excess relative risk due to mediated interaction (ereri_intmeda) 0.02 (0.01–0.03) 0.01 (0.01–0.03) 0.01 (0.01–0.02) 0.01 (0.01–0.01)
Excess relative risk due to mediation only (ereri_piea) 0.06 (0.05–0.07) 0.04 (0.02–0.07) 0.04 (0.03–0.04) 0.03 (0.02–0.03)
Total effect relative risk ratio (tereriaa) 1.54 (1.45–1.63) 1.40 (1.32–1.63) 1.60 (1.53–1.67) 1.43 (1.37–1.49)
Effects of proportion
Proportion due to neither mediation nor interaction (p_cdea) 0.68 (0.60–0.75) 0.76 (0.68–0.85) 0.83 (0.78–0.88) 0.87 (0.82–0.91)
Proportion due to interaction only (p_intrefa) 0.17 (0.10–0.24) 0.12 (0.05–0.20) 0.08 (0.04–0.11) 0.06 (0.02–0.10)
Proportion due to mediated interaction (p_intmeda) 0.04 (0.02–0.05) 0.02 (0.01–0.03) 0.02 (0.01–0.03) 0.01 (0.00–0.02)
Proportion due to mediation only (p_piea) 0.11 (0.09–0.14) 0.10 (0.07–0.12) 0.07 (0.05–0.08) 0.06 (0.04–0.07)
Overall proportion due to mediation (op_ma) 0.15 (0.12–0.17) 0.11 (0.08–0.14) 0.09 (0.07–0.10) 0.07 (0.05–0.09)
Overall proportion due to interaction (op_atia) 0.21 (0.13–0.29) 0.14 (0.05–0.23) 0.10 (0.05–0.15) 0.07 (0.02–0.12)
Overall proportion eliminated (op_ea) 0.32 (0.25–0.39) 0.24 (0.15–0.32) 0.17 (0.12–0.21) 0.13 (0.08–0.18)

Model 1, unadjusted model; model 2, adjusted for domicile, origin and parental psychiatric disorder. The upper part of the table (total effects) describes the relative risks. The lower part of the table (effects of proportion) describes the proportion of the association due to psychiatric disorders diagnosis.

a.

Terms assigned by the Stata command.