Table 5.
competing risk analyses using the Fine and Gray model for suicide mortality in patients with sepsis who were admitted to ICUs
| Variable | Death by suicide sHR (95% CI) |
P-value |
|---|---|---|
| Sex, male (versus female) | 1.37 (1.22, 1.55) | <0.001 |
| Age, years | ||
| 18–35 | 1 | |
| 36–50 | 0.84 (0.53, 1.34) | 0.470 |
| 51–65 | 0.63 (0.41, 0.97) | 0.034 |
| 65–80 | 0.61 (0.40, 0.94) | 0.024 |
| ≥ 81 | 0.77 (0.50, 1.18) | 0.230 |
| Residence at diagnosis of sepsis | ||
| Urban | 1 | |
| Rural | 1.25 (1.10, 1.42) | 0.001 |
| Income level at diagnosis of sepsis | ||
| Quartile 1 (Lowest) | 1 | |
| Quartile 2 | 0.96 (0.78, 1.19) | 0.740 |
| Quartile 3 | 1.04 (0.85, 1.26) | 0.720 |
| Quartile 4 (Highest) | 1.03 (0.87, 1.23) | 0.710 |
| Unknown | 0.95 (0.78, 1.16) | 0.630 |
| Charlson comorbidity index | ||
| 3–6 (v. −2) | 1.00 (0.85, 1.19) | 0.960 |
| 7–9 (v. −2) | 0.98 (0.84, 1.06) | 0.059 |
| −10 (v. −2) | 1.22 (1.05, 1.38) | 0.003 |
| Elixhauser comorbidity index | ||
| 8–17 (v. −7) | 1.27 (1.06, 1.52) | 0.009 |
| 18–27 (v. −7) | 1.42 (1.18, 1.72) | <0.001 |
| −28 (v. −7) | 1.86 (1.49, 2.33) | <0.001 |
| Admitting department | ||
| Medical department (versus Surgical department) | 0.34 (0.30, 0.39) | <0.001 |
| Total case volume of sepsis treatment | ||
| Quartile 1, ≤ 235 | 1 | |
| Quartile 2, 236 to < 710 | 1.22 (1.02, 1.46) | 0.028 |
| Quartile 3, 710 to < 1743 | 1.09 (0.90, 1.30) | 0.380 |
| Quartile 4, ≥ 1743 | 1.01 (0.80, 1.26) | 0.960 |
| CRRT use | 1.19 (0.99, 1.42) | 0.057 |
| Vasopressor use | 1.01 (0.89, 1.15) | 0.850 |
| ECMO support | 0.98 (0.50, 1.91) | 0.960 |
| Mechanical ventilator support | 1.81 (1.59, 2.05) | <0.001 |
| Total number of hospital admission for sepsis | ||
| 1 | 1 | |
| 2–3 | 0.77 (0.66, 0.89) | <0.001 |
| 4–5 | 0.60 (0.42, 0.88) | 0.009 |
| 6–7 | 0.73 (0.40, 1.32) | 0.300 |
| ≥ 8 | 0.33 (0.14, 0.79) | 0.013 |
| Concurrent psychiatric illness | ||
| Depression | 1.01 (0.88, 1.16) | 0.840 |
| Anxiety disorder | 0.95 (0.84, 1.08) | 0.460 |
| Substance abuse | 0.97 (0.76, 1.24) | 0.810 |
| PTSD | 2.04 (0.28, 14.62) | 0.480 |
| Bipolar | 1.19 (1.00, 1.41) | 0.046 |
| Schizophrenia or schizophrenic affective disorder | 0.97 (0.76, 1.24) | 0.810 |
| Dementia | 1.15 (1.01, 1.31) | 0.034 |
| History of Self-harm or suicidal attempt | 10.34 (3.94, 27.16) | <0.001 |
| Year of diagnosis of sepsis | ||
| 2010 | 1 | |
| 2011 | 0.85 (0.67, 1.08) | 0.190 |
| 2012 | 0.97 (0.77, 1.21) | 0.780 |
| 2013 | 1.12 (0.90, 1.40) | 0.290 |
| 2014 | 0.83 (0.66, 1.04) | 0.110 |
| 2015 | 0.82 (0.64, 1.04) | 0.110 |
| 2016 | 0.80 (0.62, 1.04) | 0.091 |
| 2017 | 0.67 (0.51, 0.89) | 0.005 |
| 2018 | 0.56 (0.42, 0.75) | <0.001 |
ICU, intensive care unit; sHR, subdistribution hazard ratio; CI, confidence interval; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; PTSD, post-traumatic stress disorder.