TABLE 1.

Approximate developmental milestones and neuropathology of nonhuman primates across the Primate Order

Species (Scientific Name)	Adult Weight (kg)	Age of maturity (years)	Lifespan (years)		Age (years) of menopause	Age assumed elderly (years)	Neuropathology
			Typical	Maximum			Naturala	Induced
Gray mouse lemur (Microcebus murinus)	0.06–0.12b	1c	5–8**d,e,f	18f	Absentd	6b	Aβ, Tau	Aβg, Taug
Common marmoset (Callithrix jacchus)	0.25–0.60i	1–1.5h	5–8*,i	22f,j	Absentk	7–8k	Aβ, Tau	Aβl,m,n
Vervet/African green monkey (Chlorocebus aethiops sabaeus)	3–9o	4–6p,q	22*o	30q,r	20p	16–18s,t	Aβ, Tau	Not studied
Macaque species
Rhesus macaque (Macaco mulatto)	5–10u,v	3–5u,v	25–27*,w,x	44y	25z	20x	Aβ, Tau	Aβaa, Taubb
Cynomolgus macaque (M. fascicularis)	3–8cc	3_5dd, ee	25–30**,ee	37g	29ff	20gg	Aβ, Tau	Aβhh
Barbary macaque (M. sylvanus)	8–18ii	4–5jj	25kk	29f,jj	25jj	20kk	Aβ, Tau	Not studied
Chimpanzee (Pan troglodytes)	35–60ll	10mm	35–50**,nn	62oo	50oo	37pp	Aβ, Tau	Not studied
Human (Homo sapiens)	60–80qq	12–16rr	yg***,SS	122tt	50–53uu	65vv	Aβ, Tau	Not studied

Note:

^*Approximate median lifespan;

^**Approximate mean lifespan;

^***Life expectancy. Absent: does not exist; not studied: no published reports.

References:

^a(Freire-Cobo et al., 2021),

^b(Languille et al., 2012),

^c(Chaudron, Pifferi, & Aujard, 2021),

^d(Perret, 1997),

^e(Hämäläinen et al., 2014),

^f(Weigl, 2005),

^g(Gary et al., 2019),

^h(Abbott & Hearn, 1978),

ⁱ(Ross, 2019),

^j(Nishijima et al„ 2012; Weigl, 2005),

^k(Abbott et al., 2003),

^l(Maclean et al., 2000),

^m(Philippens et al., 2016),

ⁿ(Ridley et al., 2006),

^o(Jorgensen, 2021) & Jorgensen pers. comm.,

^p(Atkins et al., 2014),

^q(Schmitt et al., 2018),

^r(Cramer et al., 2018),

^s(Kavanagh et al., 2019)

^t(Frye et al., 2021),

^u(van Wagenen, 1952),

^v(Plant, 2005),

^w(Tigges, Gordon, McClure, Hall, & Peters, 1988),

^x(Upright & Baxter, 2021),

^y(Stonebarger et al., 2020),

^z(Walker, 1995),

^aa(Beckman et al., 2019a),

^bb(Beckman et al., 2021),

^cc(Fa, 1989),

^dd(Luetjens & Weinbauer, 2012),

^ee(Van Esch et al., 2008),

^ff(Kavanagh et al., 2005),

^gg(Darusman et al., 2014),

^hh(Forny-Germano et al., 2014),

ⁱⁱ(Fooden, 2007),

^jj(Paul, Kuester, & Podzuweit, 1993; Weigl, 2005),

^kk(Rathke & Fischer, 2021),

^ll(Leigh & Shea, 1995),

^mm(Muller et al., 2020),

ⁿⁿ(Dyke et al., 1995),

^oo(Lacreuse et al., 2008),

^pp(Hopkins et al., 2020),

^qq(Walpole et al., 2012),

^rr(Hochberg & Konner, 2020),

^ss(Arias et al., 2020),

^tt(Robine & Allard, 1999),

^uu(Gold, 2011),

^vv(Shoven, 2007).

Abbreviation: Aβ, amyloid-beta.