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| Methods | A cost‐effectiveness analysis in the setting of the Spanish National Health System |
| Participants | Patients with COPD |
| Interventions | Tiotropium versus ipratropium or salmeterol |
| Outcomes | FEV1, quality of life (SGRQ), dyspnoea (TDI), mean stay in hospital, exacerbations and direct healthcare costs associated with hospital treatment |
| Notes |
