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. 2012 Sep 12;2012(9):CD009157. doi: 10.1002/14651858.CD009157.pub2

Schramm 2005.

Methods A cost‐effectiveness study for the Swiss public health insurance system
Participants Patients with moderate to severe COPD
Interventions Tiotropium compared to ipratropium, salmeterol or standard care
Outcomes Exacerbations, hospitalisations, direct yearly total cost for COPD therapy
Notes Pending access to full article and translation

COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; QALY: quality‐adjusted life year; SGRQ: St George's Respiratory Questionnaire; TDI: Transitional Dyspnoea Index