Table 5.

Linear regression analyses: participant age and QSM values from subcortical and cortical brain regions, with and without SNR-based correction.

QSM Reference Structure: Default MEDI TooWox
Effect	1 β	r2	p-value	SE	95% CI
Subcortical QSM	0.474	0.223	0.001**	0.024	0.036	0.132
Subcortical QSM (SNR corrected)	0.346	0.119	0.019*	0.057	0.024	0.255
Cortical QSM	0.088	0.008	0.562	0.394	−0.564	1.025
Cortical QSM (SNR corrected)	0.315	0.100	0.032*	0.013	0.003	0.056
QSM Reference Structure: Lateral Ventricles
Subcortical QSM	0.449	0.206	0.002**	0.718	0.975	3.869
Subcortical QSM (SNR corrected)	0.368	0.135	0.012*	0.202	0.123	0.937
Cortical QSM	0.045	0.002	0.762	0.045	−0.077	0.105
Cortical QSM (SNR corrected)	0.330	0.110	0.024*	0.010	0.003	0.042
QSM Reference Structure: Whole-brain WM
Subcortical QSM	0.432	0.189	0.003**	0.710	0.840	3.703
Subcortical QSM (SNR corrected)	0.202	0.041	0.176	0.444	−0.284	1.506
Cortical QSM	0.014	0.0002	0.925	0.089	−0.171	0.188
Cortical QSM (SNR corrected)	0.043	0.002	0.776	0.065	−0.112	0.150

¹Standardized coefficients.

^**p < 0.01.

^*p < 0.05.