Table 6.

Multiple comparison of mean differences of interleukin-1β levels between different time intervals in each study group using Bonferroni’s post hoc analysis

Group	Time (I)	Time (J)	Mean difference (I-J)	95% CI for difference		P
				Lower	Upper
Group 1	Before	7 days	−0.053	−0.084	−0.023	<0.001*
		30 days	−0.09	−0.125	−0.055	<0.001*
	6 months	−0.098	−0.138	−0.058	<0.001*
	7 days	30 days	−0.037	−0.056	−0.017	<0.001*
	6 months	−0.045	−0.066	−0.024	<0.001*
	30 days	6 months	−0.008	−0.018	0.001	0.11
Group 2	Before	7 days	−0.630	−0.745	−0.515	<0.001*
		30 days	−1.765	−1.961	−1.570	<0.001*
		6 months	−1.214	−1.371	−1.057	<0.001*
	7 days	30 days	−1.135	−1.333	−0.937	<0.001*
		6 months	−0.584	−0.766	−0.403	<0.001*
	30 days	6 months	0.551	0.466	0.636	<0.001*
Group 3	Before	7 days	−0.692	−0.82	−0.564	<0.001*
		30 days	−6.746	−6.991	−6.501	<0.001*
		6 months	−1.794	−2.072	−1.515	<0.001*
	7 days	30 days	−6.054	−6.245	−5.862	<0.001*
		6 months	−1.101	−1.33	−0.873	<0.001*

*Statistically significant at P<0.05. Group 1 – Control; Group 2 – Nonfluoridated group; Group 3 – Fluoridated group; CI – Class interval; P – Probability value