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. 2022 Mar 7;13:845988. doi: 10.3389/fimmu.2022.845988

Table 3.

Clinical difference between anti-MDA5 positive and anti-ARS positive patients with RP-ILD.

Variable ARS, n=70 MDA5,n=110 P value
Heliotrope sign (%) 18.6 (13/70) 73.6 (81/110) <0.001
Gottron sign (%) 31.4 (22/70) 80.9 (89/110) <0.001
V sign (%) 14.3 (10/70) 50.9 (56/110) <0.001
Shawl sign (%) 8.6 (6/70) 34.5 (38/110) <0.001
Skin ulcer (%) 1.4 (1/70) 24.5 (27/110) <0.001
CK (IU/L) 541.0 ± 1430.6 250.2 ± 747.3 0.001
ALT (IU/L) 43.4 ± 34.2 87.9 ± 89.7 <0.001
AST (IU/L) 40.3 ± 32.0 111.9 ± 241.8 <0.001
Ferritin (ng/ml) 374.7 ± 461.2 1415.3 ± 1991.1 <0.001
PBL (cell/ul) 1598.0 ± 947.2 770.6 ± 487.4 <0.001
CD3+T 1107.7 ± 655.7 548.9 ± 354.7 <0.001
CD4+T 690.4 ± 546.7 359.4 ± 249.9 <0.001
CD8+T 428.2 ± 357.8 189.2 ± 165.0 <0.001
NK 186.8 ± 189.8 39.6 ± 46.9 <0.001
NK (%) 12.1 ± 7.7 5.5 ± 5.3 <0.001
B1 (CD5+CD19+)  75.4 ± 113.4 23.2 ± 37.2 <0.001
B2 (CD5-CD19+)% 11.9 ± 8.4 19.7 ± 11.7 <0.001
BALF Mac% 14.9 ± 11.5 21.2 ± 15.5 0.090
BALF LYM% 19.3 ± 20.5 27.7 ± 25.0 0.096
BALF NE% 56.7 ± 28.6 47.6 ± 27.3 0.184

BALF Mac%, percentage of macrophage in bronchoalveolar lavage fluid; BALF LYM%, percentage of lymphocyte in bronchoalveolar lavage fluid; BALF NE%, percentage of neutrophil in bronchoalveolar lavage fluid.