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[Preprint]. 2022 Mar 17:2022.03.14.22272394. [Version 1] doi: 10.1101/2022.03.14.22272394

Table 4.

Clinical adjudication based on expert chart review in 6 patients with Possible IMX-BVN-3 bacterial scores

ID IMX-BVN-3 bacterial result IMX-BVN-3 viral result IMX-SEV-3 severity result Clinical characteristics Microbiology findings Antimicrobial therapy and other data Discharge diagnoses Bacterial infection
0076 Possible Very Unlikely Moderate Septic shock on admission Positive (C. difficile toxin in stool) Cefepime, vancomycin, fidaxomycin, metronidazole Septic shock; C. difficile colitis Co-infection
0082 Possible Possible Moderate Hypoxic respiratory failure, hypotension Negative Cefepime azithromycin, vancomycin Septic shock; bacterial pneumonia, viral pneumonia Co-infection
(bacterial pneumonia diagnosed clinically)
0281 Possible Unlikely Moderate Abdominal pain Positive (Urine culture positive for viridans streptococci) Ertapenem, cefepime, metronidazole COVID-19; abdominopelvic abscess Co-infection
(gastrointestinal perforation with peritonitis and fecal pathogens in urine)
0397 Possible Possible Moderate Hypoxic respiratory failure, persistent leukocytosis Negative Azithromycin, ceftriaxone Persistent leukocytosis Co-infection
(bacterial infection, improved with antibiotics suspected by ID consult)
0477 Possible Possible Moderate Shortness of breath, hypoxia, SIRS Negative Eefepime, caspofungin Sepsis; Leukemia with graft vs. host disease Co-infection
(bacterial infection, treated with antibiotics suspected by ID consult)
0500 Possible Very Unlikely Moderate Fall Negative None used on admission Asymptomatic COVID-19 infection Negative