Table 4.
Clinical adjudication based on expert chart review in 6 patients with Possible IMX-BVN-3 bacterial scores
| ID | IMX-BVN-3 bacterial result | IMX-BVN-3 viral result | IMX-SEV-3 severity result | Clinical characteristics | Microbiology findings | Antimicrobial therapy and other data | Discharge diagnoses | Bacterial infection |
|---|---|---|---|---|---|---|---|---|
| 0076 | Possible | Very Unlikely | Moderate | Septic shock on admission | Positive (C. difficile toxin in stool) | Cefepime, vancomycin, fidaxomycin, metronidazole | Septic shock; C. difficile colitis | Co-infection |
| 0082 | Possible | Possible | Moderate | Hypoxic respiratory failure, hypotension | Negative | Cefepime azithromycin, vancomycin | Septic shock; bacterial pneumonia, viral pneumonia | Co-infection (bacterial pneumonia diagnosed clinically) |
| 0281 | Possible | Unlikely | Moderate | Abdominal pain | Positive (Urine culture positive for viridans streptococci) | Ertapenem, cefepime, metronidazole | COVID-19; abdominopelvic abscess | Co-infection (gastrointestinal perforation with peritonitis and fecal pathogens in urine) |
| 0397 | Possible | Possible | Moderate | Hypoxic respiratory failure, persistent leukocytosis | Negative | Azithromycin, ceftriaxone | Persistent leukocytosis | Co-infection (bacterial infection, improved with antibiotics suspected by ID consult) |
| 0477 | Possible | Possible | Moderate | Shortness of breath, hypoxia, SIRS | Negative | Eefepime, caspofungin | Sepsis; Leukemia with graft vs. host disease | Co-infection (bacterial infection, treated with antibiotics suspected by ID consult) |
| 0500 | Possible | Very Unlikely | Moderate | Fall | Negative | None used on admission | Asymptomatic COVID-19 infection | Negative |