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Inhibition of intracellular parasite growth in vitro by DMC after encapsulation in PLA. L. amazonensis-infected macrophages were cultured for 48 h in the presence of 1 μg of free DMC/ml, 5 μg of empty PLA nanoparticles/ml, or the same concentrations of DMC-PLA. Control, medium alone. The percentages of infected macrophages are given inside the bars. The P value of DMC-PLA in relation to DMC is given. Results are means ± standard deviations (SD) (n = 3).
