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. 2022 Mar 7;9:795074. doi: 10.3389/fmed.2022.795074

Table 3.

Variables associated with desaturation in the six-minute walk test (6MWT) 6-months after hospital discharge.

Variables Present
(n = 15)
Absence (n = 29) p-valuea RR
(IC 95%)b
Age, years, mean (SD) 56 (10) 52.7 (11) 0.24 NA
Gender
Male, n (%) 6 (40) 25 (86) 0.001* 0.13 (0.03–0.6)
BMI, mean (SD) 32 (6.8) 30 (3.8) 0.52 NA
Extent of lung involvement at admissionc n (%)
25–50% 4 (27) 12 (50) 0.08 NA
>50% 11 (73) 12 (50)
Charlson Comorbidity Index, median (25–75) 1 (1, 2) 2 (1–3) 0.044* 1.5 (0.8–2.9)
SAPS III, mean (SD) 53 (15.0) 46 (10.1) 0.15 NA
Respiratory SOFA
D1, mean (SD) 2.9 (1.2) 2.7 (0.9) 0.50 NA
D3, mean (SD) 2.6 (1.1) 1.8 (1.5) 0.045* 1.06 (0.8–1.4)
SOFA
D1, mean (SD) 3.6 (1.7) 3.6 (1.7) 0.73 NA
D3, mean (SD) 3.6 (2.8) 2.4 (2.4) 0.15 NA
C-reactive protein, mg/L
D1, mean (SD) 88 (45) 136 (96) 0.07 NA
D3, mean (SD) 91 (89) 122 (102) 0.40 NA
ICU, yes, n (%) 11 (73) 20 (69) 0.76 NA
ICU length of stay, days, mean (SD) 14 (8.0) 10 (9.6) 0.279 NA
Mechanical ventilation, yes, n (%) 4 (27) 6 (21) 0.65 NA
Days on mechanical ventilation, mean (SD) 15 (5.3) 11 (9.2) 0.750 NA
Length of hospital stay, days, mean (SD) 20 (10.3) 14 (9.9) 0.485 NA

SD, standard deviation; RR- Relative Risk; CI, confidence interval; NA, not applied; BMI, Body mass index; SAPS III, Simplified Acute Physiology Score 3; SOFA, sequential organ failure assessment score; ICU, intensive care unit; N, number of participants.

*

p < 0.20 and included in the binary logistic regression.

a

p-value from the univariate analysis.

b

RR form the regression analysis.

c

For five patients, CT scan was not performed at hospital admission.