Table 4.
Variables associated with a decreased forced expiratory volume in one second 6-months after hospital discharge.
| Variables |
Present
(n = 8) |
Absence (n = 36) | p-valuea |
|---|---|---|---|
| Age, years, mean (SD) | 60 (5) | 53 (11) | 0.015* |
| Gender | |||
| Male, n (%) | 6 (75) | 25 (10) | 0.75 |
| BMI, mean (SD) | 32 (5.4) | 30 (5.0) | 0.35 |
| Extent of lung involvement at admissionb n (%) | |||
| 25–50% | 0 (0.0) | 15 (48) | 0.029* |
| >50% | 7 (100) | 16 (52) | |
| Charlson Comorbidity Index, median (25–75) | 1 (1, 2) | 2 (2) | 0.11 |
| SAPS III, mean (SD) | 50 (15.2) | 48 (12.0) | 0.71 |
| Respiratory SOFA | |||
| D1, mean (SD) | 2.9 (1.2) | 2.8 (0.9) | 0.80 |
| D3, mean (SD) | 2.0 (1.4) | 2.1 (1.4) | 0.87 |
| SOFA | |||
| D1, mean (SD) | 3.9 (2.8) | 3.7 (1.7) | 0.81 |
| D3, mean (SD) | 2.6 (2.1) | 2.9 (2.8) | 0.76 |
| C-reactive protein, mg/L | |||
| D1, mean (SD) | 108 (103) | 122 (80) | 0.70 |
| D3, mean (SD) | 129 (172) | 103 (70) | 0.72 |
| ICU yes, n (%) | 5 (62) | 26 (72) | 0.59 |
| ICU length of stay, days, mean (SD) | 14 (11.6) | 11 (8.7) | 0.51 |
| Mechanical ventilation, yes, n (%) | 2 (25) | 8 (22) | 0.86 |
| Days on mechanical ventilation, mean (SD) | 18 (7.8) | 11 (7.4) | 0.25 |
| Length of hospital stay, days, mean (SD) | 19 (11.3) | 15 (10.0) | 0.35 |
SD, standard deviation; BMI, Body mass index; FEV1, forced expiratory volume in one second; SAPS III, Simplified Acute Physiology Score 3; SOFA, sequential organ failure assessment score; ICU, intensive care unit; N, number of participants.
a
p-value from the univariate analysis.
b
For six patients CT scan was not performed at hospital admission.
*
Due to the low number of events, it was not possible to perform binary regression analysis.