Table 2.

Association between visit-to-visit heart rate variability and composite cardiovascular outcomes in different models.

VVHRV	Hazard ratio (95% CI) P-value
	Model 1	Model 2	Model 3
CV in heart rate
T1	Ref.	Ref.	Ref.
T2	1.17 (0.93, 1.48) P = 0.18	1.20 (0.95, 1.52) P = 0.13	1.105 (0.91, 1.47) P = 0.25
T3	2.09 (1.70, 2.59) P < 0.001	2.09 (1.69, 2.58) P < 0.001	2.09 (1.68, 2.59) P < 0.001

Model 1 adjusted for none.

Model 2 adjusted for age, sex, race and treatment arms.

Model 3 adjusted for age, sex, race, treatment arms, baseline systolic BP, baseline heart rate, smoking status, eGFR, serum creatinine, urine albumin/creatinine ratio, fasting triglycerides, Framingham 10-y CVD risk score, prior CVD and prior CKD.