Table 3.

Continuous Association between visit-to-visit heart rate variability and composite cardiovascular outcomes in different models.

VVHRV	Hazard ratio (95%CI) P-value
	Model 1	Model 2	Model 3
HRCV (per 1 CV increment)		P for interaction = 0.248	P for interaction = 0.390
Total	1.05 (1.04, 1.06) P < 0.001	1.04 (1.03, 1.05) P < 0.001	1.04 (1.03, 1.05) P < 0.001
Standard BP control	1.04 (1.02, 1.06) P < 0.001	1.03 (1.01, 1.05) P < 0.001	1.03 (1.01, 1.06) P < 0.001
Intensive BP control	1.05 (1.04, 1.07) P < 0.001	1.05 (1.03, 1.06) P < 0.001	1.04 (1.03, 1.06) P < 0.001

Model 1 adjusted for none.

Model 2 adjusted for age, sex, race.

Model 3 adjusted for age, sex, race, baseline systolic BP, baseline heart rate, smoking status, eGFR, serum creatinine, urine albumin/creatinine ratio, fasting triglycerides, Framingham 10-y CVD risk score, prior CVD and prior CKD.