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. 2022 Mar 21;17(3):e0265560. doi: 10.1371/journal.pone.0265560

Table 2. Summary of characteristics of included studies showing relation between screen time (ST) and Metabolic syndrome (MetS).

Author; publication year Country Study design; Sample size (N) Mean age at baseline (SD); gender Screen type Exposure
ST measure
Outcome measures (MetS) Association with MetS
OR (95%CI)
Comments
Schaan et al. (2019) [36] Brazil 33,900; cross-sectional 14.6 year (SD not reported); 59.4% Female TV view, computers, videogames Self-reported hours per day IDF guidelines (WC, SBP, DBP, Fasting blood glucose, Triglycerides; HDL) ST ≥6 h/day; 1.68 (1.03–2.74). Prevalence of MetS 2.6% (95%CI: 2.3–3.0), ST remained significantly associated with MetS after adjusting of covariates; age, sex, socioeconomic, PA.
Association remained significant MetS remained significant only for adolescents who reported consumption of snacks in front of screens.
Khan M et al. (2019) [32] UAE 474; cross-sectional 14.9 ±1.9 years; 47% Female Computer, television, and video game Self-reported hours per day IDF guidelines (WC, SBP, DBP, Fasting blood glucose, Triglycerides; HDL) ST ≥2 h/day: 2.20 (1.04–4.67)
Each hour of increased ST (1.21; 1.08–1.35)
Prevalence of MetS 8.5% in <2hr/d, 13.4% ≥2 hr/d)
Association was adjusted for age, sex, physical education classes, smoking, parental education, daily intake of carbonated drink, fruits, vegetables, milk, fast food
Mark E and Janssen (2008) [37] US 1803; cross- sectional 15.9 ± 2.2 years; 50.3% Female TV, video, computer game Self-reported hours per day home interview/ mobile exam centre NCEP ATP II: ≥3 of the following: high triglycerides, high fasting glucose, high WC, high BP, low HDL. ST ≥5 h/day: 2.90 (1.39–6.02) Prevalence of MetS 3.7% in≤1 hr/d, 8.4% in ≥5 hr/day.
Association was adjusted for age, smoking and PA.
Kang HT et al. (2010) [38] Korea 845, cross-sectional 13.4 ± 2.5 years; 46.9% Female TV time, computer game, internet Self-reported hours per week NCEP ATP II: ≥3 of the following: high triglycerides, high fasting glucose, high WC, high BP, low HDL. ST (≥35 h/week: 2.23 (1.02–4.86) Prevalence of MetS 7.3%.
Association was adjusted for age, sex, household income, residence area.
de Oliveira RG et al. (2014) [31] Brazil 1,035, cross-sectional Mean not reported; 56.6% of (12-15y), 43.4% of (16-20y), 54.6% Female TV, computer, video game, tablet, smartphone Self-reported hours per day IDF guidelines (WC, SBP, DBP, Fasting blood glucose, Triglycerides; HDL) ST> 2 h/day: 1.32 (1.07–1.94) Prevalence of MetS 4.5% (95% CI: 3.8–5.4).
Association was adjusted for demographic, anthropometric nutritional indicators and, lifestyle determinants.
Siwarom S et al. (2021) [39] Thailand 1934, cross-sectional 13.40 ± 1.94; 49.7% Female television watching, computer, smart phone, tablet use Self-reported hours per week/screen media exposure during the first 2 years of life IDF, Cook’s, and de Ferranti’s. MetS by 1 out of 3 definitions:
Exposure to screen media during the first 2 years of life: 1.30 (1.01–1.68).
No association between total ST & MetS: 1.00 (0.99–1.00)
Prevalence of MetS 17%, Association of ST and MetS was adjusted for age, sex, foot intake, fruits and vegetables, PA.
Hardy L et al. (2010) [40] Australia 496, cross-sectional 15.4 ± 0.4 year; 42% Female watching television/DVDs/videos and using a computer for recreation Self-reported hours per day.
Adolescent Sedentary Activity Questionnaire
Metabolic risk factors:
Insulin level
Glucose level
HOMA-IR, HDL-C, LDL-C, Triglyceride, hs-CRP, ALT, GGT l, SBP, DBP
ST ≥2 h/day
Boys: HOMA-IR (adjusted OR, 2.42 (1.11–5.28), insulin levels (adjusted OR, 2.73 (1.43–5.23)
Girls: no association
Prevalence of abnormal biomarker e.g., Insulin in ≥2h/d is 22.7% boys vs, 22.9% girls; HOMA-IR 41.5% boys vs. 46.5% girls.
Association was adjusted for BMI, SES (IRDS score), EDNP food score, Tanner score, and CRE (number of laps)
Fadzlina A et al. (2014) [41] Malaysia 1014, cross-sectional 12.88 ± 0.33 years; 61.8% Female Not reported Self-reported hours per day IDF guidelines (WC, SBP, DBP, Fasting blood glucose, Triglycerides; HDL) No association between ST and MetS Prevalence of MetS 2.6%in total, 10% among overweight. Obese
No adjusted model was utilized
Grøntved A et al. (2020) [42] EYHS, Danish cohort 435, cohort 15.6 ± 0.4 year; 54.5% Female TV, computer use Self-reported hours per day MetS z-score based on AHA/NHLBI; WC, SBP, DBP, triglycerides, HDL (inverted), fasting glucose, fasting insulin Total ST > 2 h/day a/w MetS z-score. 0.35 (0.08–0.62)
Each 1-hour increment in TV viewing time; syndrome z-score 0.45 (0.14–0.76)
MetS Z-score for ≤1h (−0.2 ± 2.6), 1-3h (−0.1 ± 2.5)
>3 h were (1.2 ± 3.5)
Adjusted for age, gender, cohort, parental education level, current smoking status, (MVPA), intake of soft drinks, fruit- and vegetable intake, and family history of cardiovascular disease.
de Castro Silveira et al. (2020) [43] Brazil 1200, cross-sectional Up to 17 years, no mean age reported; 56% Female Not reported Self-reported hours per day Continuous metabolic score (CMetS) > 1 as metabolic risk factor
Z-score of WC, SBP, glucose, triglyceride, total cholesterol, LDL, HDL
ST ≥2 h/day; Prevalence Ratio (PR) = 0.99 (0.95–1.03), insignificant association Prevalence of metabolic risk 14.7%.
ST was adjusted for cardiorespiratory fitness measured at time of recruitment yielded significant association.

Abbreviations: IDF, International Diabetes Federation, NCEP ATP II, National Cholesterol Education Program Adult Treatment Panel; SD, Standard deviation; WC, Waist circumference; SBP, systolic blood pressure, DBP, diastolic blood pressure, PA, physical activity, BMI, Body mass index; SES, socioeconomic status; IRDS, Australian Bureau of Statistics Index of Relative; EDNP, energy-dense nutrient-poor; CRE, cardiorespiratory endurance. EYHS, European Youth Heart Study; AHA, American Heart Association (AHA); NHLBI, and the National Heart, Lung, and Blood Institute. HDL-C, high density lipoprotein cholesterol, LDL-C, low density lipoprotein cholesterol; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; h-s CRP, high sensitivity C-reactive protein; ALT, Alanine Aminotransferase; GGT, Gamma-Glutamyl Transferase.