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. 2022 Feb 15;16(6):1402–1419. doi: 10.1002/1878-0261.13184

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© 2022 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — Regulatory network and biological processes associated with miR‐200a/b/‐429. (A) miR‐200a/‐b/‐429 regulatory network. Each miRNA in the miR‐200a/‐b/‐429 cluster is used as node. The interaction partners are their potential target genes, identified from correlation analysis of miRNA and gene expression in the explorative cohort (n = 90) and validation cohort 1 (n = 110). The network was visualized using cytoscape software v3.6.1. (B) Enriched KEGG pathways and GO terms in the list of 225 potential miR‐200a/b/‐429 target genes. Y‐axis denotes significance level from the functional annotation tool david v6.8.