Table 2.

Cox regression analysis of tumor recurrence at different sites for 200 patients. N.S, nonsignificant.

Factor	Univariate analysis a			Multivariate analysis b
	P	HR	95% CI	P	HR	95% CI
Central pelvic control c
Lymph node status	1.3 × 10−2	5.15	1.42–18.73	2.8 × 10−2	4.67	1.18–18.54
Tumor volume d	(6.3 × 10−2)	3.06	0.94–9.97	N.S	–	–
FIGO stage e	(1.0 × 10−1)	2.56	0.83–7.85	N.S	–	–
Hypoxia status f	3.4 × 10−3	6.87	1.89–25.00	1.9 × 10−2	4.78	1.29–17.74
miR‐200a/b/‐429 score	6.3 × 10−3	0.45	0.25–0.80	1.1 × 10−2	0.43	0.23–0.83
Lateral pelvic control c
Lymph node status	9.9 × 10−3	7.37	1.61–33.67	4.8 × 10−2	4.81	1.01–22.85
Tumor volume d	1.5 × 10−2	6.56	1.40–30.00	N.S	–	–
FIGO stage e	8.6 × 10−3	7.74	2.23–25.84	8.3 × 10−3	5.27	1.53–18.15
Hypoxia status f	(7.6 × 10−2)	2.81	0.89–8.87	N.S	–	–
miR‐200a/b/‐429 score	N.S	–	–	–	–	–
Distal control c
Lymph node status	1.1 × 10−2	2.39	1.22–4.68	N.S.	–	–
Tumor volume d	7.2 × 10−4	3.53	1.70–7.32	3.0 × 10−2	2.35	1.09–5.08
FIGO stage e	2.0 × 10−6	5.05	2.61–9.77	1.6 × 10−4	3.82	1.90–7.68
Hypoxia status f	(6.5 × 10−2)	1.85	0.96–3.57	N.S.	–	–
miR‐200a/b/‐429 score	N.S	–	–	–	–	–

Results for the miR‐200a/b/‐429 score are highlighted in bold.

^a Variables with P > 0.05 and ≤ 0.1 in the univariate analysis are shown in parentheses.

^b Variables with P ≤ 0.1 in the univariate analysis were included in multivariate analysis. The same results were obtained for forward and backward selection.

^c Site of recurrence was unknown for three patients.

^d Patients were divided into two groups based on the median tumor volume of 36.6 cm³.

^e Patients were divided into two groups based on FIGO stage IB–IIB or IIIA–IVA.

^f Patients were divided into two groups based on a less hypoxic or more hypoxic tumor.