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. 2022 Mar 7;13:817596. doi: 10.3389/fphar.2022.817596

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Copyright © 2022 Yuan, Hu, Liu, Xie, Yang, Li, Zhang, Chen, Tang and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DCL mitigates DSS-induced intestinal barrier injury in mice. Representative PAS images (A) and the mean of IOD (B) of colon sections in each group. Representative immunohistochemical images and the relative expression of ZO-1 (C) and Occludin (D) are shown. Scale bar = 200, 100, and 20 μm. The brown areas indicate positive areas. Data are represented as mean ± SEM, n = 6. ^# p < 0.05, ^## p < 0.01, ^### p < 0.001, ^#### p < 0.0001 compared to normal group. ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001, ^**** p < 0.0001 compared to DSS group.