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. 2022 Mar 7;13:817596. doi: 10.3389/fphar.2022.817596

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Copyright © 2022 Yuan, Hu, Liu, Xie, Yang, Li, Zhang, Chen, Tang and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DCL represses intestinal inflammation of DSS-induced colitis in mice. The representative immunohistochemical images and the relative expression of CD68 (A) and MPO (B) in colon tissues from each group. The effects of DCL on the expression of TNF-α (C) and IL-6 (D) in DSS- challenged mice. Scale bar = 20 and 100 μm. The brown areas indicate positive areas. Data are represented as mean ± SEM, n = 6. ^# p < 0.05, ^## p < 0.01, ^### p < 0.001, ^#### p < 0.0001 compared to normal group. ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001, ^**** p < 0.0001 compared to DSS group.