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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Cancer Res. 2021 Nov 4;82(1):169–176. doi: 10.1158/0008-5472.CAN-21-1467

Fig. 3. Neoadjuvant chemotherapy is not associated with the acquisition of somatic mutations.

Fig. 3.

(A) Oncoprint of all somatic mutations detected in at least two patient samples. Left upper triangle in each square corresponds to pre-NACT sample and right lower triangle corresponds to post-NACT tissue. Mutational types are indicated by color. The frequency of mutations within our cohort is compared to the frequency of mutations in the TCGA analysis of HGSOC. VAF = variant allele frequency. (B) Proportion of each mutational class in all coding genes detected in the entire patient cohort, divided based on pre or post –NACT.