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. 1999 Jul;43(7):1798–1802. doi: 10.1128/aac.43.7.1798

TABLE 2.

Pharmacokinetics of ceftazidime in critically ill patients and historical controls

Subjects Mean (SD)a
AUC (mg · h/liter) CL (liter/h) Vβ (liters) t1/2β
Study patients 277.31 (138.98)b 9.06 (4.79) 56.91 (25.93)* 4.75 (1.85)*
Historical controlsd 153.5 (23.1)c 6.64 (0.97) 13.6 (1.9)* 1.8 (0.14)*
a

*, P < 0.001 by the unpaired t test. 

b

AUCSS

c

AUC from 0 h to infinity after a 1-g i.v. dose. 

d

Data for controls are from reference 27