TABLE 1.
MICs of OMGE constituents and antibiotics for H. pylori
| Compound | MICa (μg/ml) for:
|
||
|---|---|---|---|
| ATCC 43504 | ATCC 43579 | ATCC 43629 | |
| Ajoenes | |||
| Z-Ajoene | 20 | 20 | 15 |
| E-Ajoene | 25 | 25 | 25 |
| Z-10-DA | 15 | 20 | 15 |
| Iso-E-10-DA | 10 | 15 | 10 |
| Vinyldithiins | |||
| 2-Vinyl-4H-1,3-dithiin | >100 | >100 | >100 |
| 3-Vinyl-4H-1,2-dithiin | >100 | >100 | >100 |
| Thiosulfinates | |||
| AllS(O)SPn-(Z,E) | >100 | >100 | >100 |
| AllS(O)SMe | 25 | 20 | 25 |
| AllS(O)SAllb | 20 | 30 | 30 |
| Antibiotics | |||
| Amoxicillin | 0.025 | 0.025 | 0.025 |
| Clarithromycin | 0.005 | 0.01 | 0.03 |
| Metronidazole | 3.2 | 1.6 | 1.6 |
a
Mean of five determinations.
b
Allicin [AllS(O)SAll] is not a constituent of OMGE.