Table 3.
Characteristics of PLGA NSs Unloaded/Loaded with GPS Prepared by Single Emulsion Solvent Evaporation Method
| Formula Key | Particle Size (nm) | Polydispersity Index (PDI) | Zeta Potential (mV) | % EE |
|---|---|---|---|---|
| F1 | 123.72±07.81 | 0.098±0.021 | −5.84±0.84 | 55.78±3.74 |
| F2 | 158.79±05.56 | 0.128±0.023 | −7.23±0.92 | 64.24±4.84 |
| F3 | 189.75±10.42 | 0.139±0.016 | −6.45±0.73 | 70.12±2.78 |
| F4 | 223.15±15.78 | 0.117±0.065 | −11.84±1.45 | 69.08±3.87 |
| F5 | 250.10±07.86 | 0.145±0.054 | −12.75±2.41 | 83.35±5.71 |
| F6 | 288.73±09.85 | 0.174±0.087 | −14.89±3.71 | 87.74±6.98 |
| F7 | 292.43±17.42 | 0.135±0.079 | −17.52±3.12 | 77.84±5.82 |
| F8 | 345.9±15.25 | 0.198±0.081 | −19.45±2.89 | 85.89±3.69 |
| F9 | 387.93±14.75 | 0.203±0.096 | −18.74±4.78 | 87.99±5.71 |
| Unloaded Placebo NSs | ||||
| P2 | 127.78±8.79 | 0.082±0.021 | − 8.95±0.74 | – |
| P5 | 197.82±4.56 | 0.115±0.029 | −14.89±0.81 | – |
| P8 | 305.89±9.53 | 0.168±0.032 | −21.63±0.92 | – |