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. 2022 Mar 21;28(3):513–516. doi: 10.1038/s41591-022-01735-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 8 — Phased parent genomes and parental support (PS) embryo genotypes are used to reconstruct the embryo’s genome at euploid chromosomes. The phased parent genomes are determined in Extended Data Fig. 7. One parent’s (parent 1) transmitted haplotypes are shown in pink (labeled 1 and 2) and the other parent’s (parent 2) phased haplotypes are shown in purple (labeled 3 and 4). In step 1, the embryo’s PS genotype determines which parental haplotype is transmitted to the embryo (dotted line). Missing data in the embryo or the parents’ phased genomes is excluded. In step 2, positions where genotypes are available from both parents are combined to create the predicted embryo genome; positions with missing data are excluded.