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. 2022 Mar 22;119:69–76. doi: 10.1016/j.ijid.2022.03.028

Table 2.

Vaccine effectiveness against COVID-19 infection by vaccine type and duration since full vaccination

‘Late'
(Fully Vaccinated in July to August)
‘Early'
(Fully Vaccinated in April to June)
Total Person-days at risk Incidence rates/1,000 persons VE CI (95%) Total Person-days at risk Incidence rates/1,000 persons VE CI (95%)
COVID-19 Infection
Overall Unvaccinated 81,987 46,811,305 1.751 ref ref 81,987 46,811,305 1.751 ref ref
BNT162b2 30,070 136,056,979 0.221 90.8 89.4, 92.1 21,888 41,756,536 0.524 79.3 76.1, 82.1
CoronaVac 104,747 141,155,066 0.742 74.5 70.6, 78.0 6,039 3,843,839 1.571 30.4 18.8, 40.3
Age Group
(in years)
15 to 39 Unvaccinated . . . . . . ref ref . . . . . . ref ref
BNT162b2 . . . . . . 91.9 90.2, 93.3 . . . . . . 86.1 83.2, 88.5
CoronaVac . . . . . . 73.9 68.4, 78.5 . . . . . . 67.3 60.1, 73.3
40 to 59 Unvaccinated . . . . . . ref ref . . . . . . ref ref
BNT162b2 . . . . . . 88.9 86.5, 90.9 . . . . . . 77.3 72.3, 81.3
CoronaVac . . . . . . 70.5 64.1, 75.7 . . . . . . 32.4 16.7, 45.2
≥60 Unvaccinated . . . . . . ref ref . . .. .. ref ref
BNT162b2 . . . . . . 90.9 89.1, 92.4 . . . . . . 69.8 63.7, 74.9
CoronaVac . . . . . . 78.6 74.4, 82.2 . . . . . . -38.6 -68.4, -14.1

Abbreviations: CI, confidence intervals; COVID-19, coronavirus disease; VE, vaccine effectiveness; BNT162b2, Pfizer-BioNTech; CoronaVac, Sinovac.

The estimates were adjusted for age, gender and states of residence

The analysis compared between the ‘Late’ group, individuals vaccinated in July–August 2021 (1 to 2 months after vaccination during the outcomes observation period in September 2021), and the ‘Early’ group, individuals vaccinated in April–June 2021 (3–5 months after vaccination), and unvaccinated individuals by August 31st, 2021, who act as the baseline